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Posted: Thu Dec 13, 2007 6:16 pm
by jaysawatzki
Ness wrote:Also, LSD doesn't burn holes in your brain. LSD acts as a 5-HT2a receptor agonist and also binds to some receptors in your dopamine and norepinephrine systems.
Close. I have a degree in neuroscience, and I can tell you that it binds to the actual neuro
transmitters like dopamine and inhibits their ability to be absorbed by MAO's. For example MJ lets the receptors produce and give off more dopamine. Dopamine is harmless, but the point I am getting to here is that noradrenaline (norepinephrine) IS harmful, and high doses of LSD can cause a imbalance in ratios such as the Dopamine to Serotonin. High levels of noradrenaline can also cause a huge increase in heart rate, increasing blood pressure and CAN cause vessels to explode in your brain, on top of that it impairs your ability's to regulate heat. And in theory CAN crudely "burn holes" in your brain when directly applied through powder or inject forms, (I am not a believe in this.) It's pretty theoretical. Anyway, the point is, high levels of noradrenaline is BAD. On the contrast, high levels of dopamine is bliss
.
Posted: Thu Dec 13, 2007 7:58 pm
by Ness
Yeah, well, I suppose that's why you don't take epic doses of acid on a daily basis. AFAIK, neurotoxicity caused by LSD has never been demonstrated, so if it IS potentially neurotoxic, doses far higher than the already ridiculously high doses used in the studies would be required. LSD is utterly non-toxic at recreational doses.
Posted: Thu Dec 13, 2007 11:25 pm
by jaysawatzki
Ness wrote:Yeah, well, I suppose that's why you don't take epic doses of acid on a daily basis. AFAIK, neurotoxicity caused by LSD has never been demonstrated, so if it IS potentially neurotoxic, doses far higher than the already ridiculously high doses used in the studies would be required. LSD is utterly non-toxic at recreational doses.
Yup, exactly. As I said before, LSD is fairly nontoxic. Although as with all drugs there are risks that can happen. LSD has been studied to death by so many people, it is the most commonly researched drug by far, so in rec. doses your fine, but be careful, if you start to feel like your heart is racing and your blood pressure is over 175, i'd call 911. Although if you DO want a perma-high, hell keep it going. LOL. There have been many cases of people having "highs" that last for days and months. Again, just use caution as with any drug.
Posted: Thu Dec 13, 2007 11:54 pm
by familyguy
fanor45 wrote:WOW, lol lsd does NOT burn holes in your brain, some people are so gullible...what did the schools tell you that? drugs can be okay, if you use them correctly, and are safe with them..tell me you can't be safe with a drug, can you really even be safe driving your car? no. you cant. you have more of a chance dieing from your car, than a plane crash...
looks like you just got proved wrong dumbfuck.
Posted: Fri Dec 14, 2007 12:05 am
by Ness
familyguy wrote:fanor45 wrote:WOW, lol lsd does NOT burn holes in your brain, some people are so gullible...what did the schools tell you that? drugs can be okay, if you use them correctly, and are safe with them..tell me you can't be safe with a drug, can you really even be safe driving your car? no. you cant. you have more of a chance dieing from your car, than a plane crash...
looks like you just got proved wrong dumbfuck.
Where?
Posted: Sat Dec 15, 2007 3:21 pm
by jaysawatzki
familyguy wrote:fanor45 wrote:WOW, lol lsd does NOT burn holes in your brain, some people are so gullible...what did the schools tell you that? drugs can be okay, if you use them correctly, and are safe with them..tell me you can't be safe with a drug, can you really even be safe driving your car? no. you cant. you have more of a chance dieing from your car, than a plane crash...
looks like you just got proved wrong dumbfuck.
Ehh, he sure as hell isn't correct, but he's not entirely wrong. SOME drugs are OK if used CORRECTLY. But tell me is using a drug at all using it correctly other than using it for it's original intentions? I can see how MJ is used with out bad effects, because it really is meant to be "abused." Where taking regulated use of Cocaine for medical reasons can be ok, who the hell abuses Cocaine in regulation? no one. My point is, drugs are abused to the point of no return. Most people do studies on drugs to show their MEDICAL effect, not their recreational effects. Heroin is a great example of that. It is used to cure Morphine addiction, and when used to do so, it is perfectly fine. But when abused, and done over and over again in 20 times the normal dose, you have problems of vein trouble, etc. Same with LSD. Sure, once in a while it's fine, but when you start tampering, like most abusers do, you are going to get problems like the crudely put "holes in your brain." Anyway, all I am saying is no abuser is "safe" with their drug usage as this guy says.
Posted: Sat Dec 15, 2007 3:33 pm
by Ness
jaysawatzki wrote:familyguy wrote:fanor45 wrote:WOW, lol lsd does NOT burn holes in your brain, some people are so gullible...what did the schools tell you that? drugs can be okay, if you use them correctly, and are safe with them..tell me you can't be safe with a drug, can you really even be safe driving your car? no. you cant. you have more of a chance dieing from your car, than a plane crash...
looks like you just got proved wrong dumbfuck.
Ehh, he sure as hell isn't correct, but he's not entirely wrong. SOME drugs are OK if used CORRECTLY. But tell me is using a drug at all using it correctly other than using it for it's original intentions? I can see how MJ is used with out bad effects, because it really is meant to be "abused." Where taking regulated use of Cocaine for medical reasons can be ok, who the hell abuses Cocaine in regulation? no one. My point is, drugs are abused to the point of no return. Most people do studies on drugs to show their MEDICAL effect, not their recreational effects. Heroin is a great example of that. It is used to cure Morphine addiction, and when used to do so, it is perfectly fine. But when abused, and done over and over again in 20 times the normal dose, you have problems of vein trouble, etc. Same with LSD. Sure, once in a while it's fine, but when you start tampering, like most abusers do, you are going to get problems like the crudely put "holes in your brain." Anyway, all I am saying is no abuser is "safe" with their drug usage as this guy says.
I'm sorry, but you're just plain wrong all around. What you're saying is tantamount to saying that all black people are criminals, all Mexicans are lazy, and Chinese people can't drive. And MANY studies are done on the effects of recreational drug use. In fact, the studies that were done with LSD used doses *
FAR* above recreational doses. In fact, most studies done on recreational drug use use doses far, far above recreational doses with frequency far above normal use patterns. Heroin isn't used to treat morphine addiction, methadone and suboxone are used to treat opioid addiction of any kind, usually heroin. And even long-term opioid abuse is fine, ignoring the problems caused by using IV as your MOA. Not all users turn to IV use. there are a GREAT many responsible, safe drug users, myself included. And I am going to repeat, no amount of LSD use is going to burn holes in your brain or, in fact, cause ANY physical damage. In one government study, a person was given LSD every day for 77 days straight. He was fine. I'm sure that the person was permanently changed, but that is a result of the experience itself, NOT damage caused by the drug.
Wow...these drugies...
Posted: Sat Dec 15, 2007 6:18 pm
by chmsalman
Okay...you guys are completely insane. I have never done any drugs before...ive never touched a cigarette, and i havent even had a sip of alcohol. im absolutely drug free. Thats caz i know what all that shit can do to me.
Its impossible to get a person who does drugs to say that they are harmful to you because they want to think that. So any of you who think the drugies who are posting on this thread are complete idiots...they are...and you posting against them will never really make them say that drugs fuck u up...even though they do...and thats what they were really made for.
who do you think theyre illegal??
Posted: Sat Dec 15, 2007 6:44 pm
by Ness
Irresponsible drug abuse is BAD FOR YOU! Abusing ecstasy will turn you into a depressed e-tard. Blowing coke all day every day will fuck up your dopamine system. Shooting heroin will collapse your veins. yeah, drug abuse is bad for you. There is, however, a huge difference between being a recreational drug user and being a drug abuser. Illegal and legal don't mean a damn thing when it comes to pharmacology. Things are how they are, the law has no impact on it. So, you've never smoked tobacco or drank alcohol. Yay. What, do you want a medal? Don't you come in here all high and mighty and clump all users into the same category, because we are not all the same. There are a lot of different reasons why drugs are illegal, the LEAST of which is because they are "bad for you". Among all of the recreational drugs, legal and illegal, tobacco and alcohol are near the top of the list as far as "bad for you" goes. Whether you want to admit it or not, pharmacologically speaking, LSD is much, much better for you than tobacco or alcohol. I'm here stating pure facts, the good and the bad. Ask me what the health risks of using a certain drug are and I will tell you in FULL. I am utterly unbiased when it comes to drugs, it just appears that I am bias in their favor because I have to CONTINUALLY disprove myths and misconceptions about them. Ask me any question about any drug and I will give you the absolute true, full answer.
Posted: Sat Dec 15, 2007 7:42 pm
by chmsalman
see...i just proved my point. You can never get a drugie to tell you that drugs are bad for you. Mentality doesnt work that way. The drugie himself will think of ways to prove to you that drugs are "good for you" or "not bad for you".
Every school atleast in north america probably teaches students about how its bad for you to inhale smoke that comes out of cigaretts. They spend billions of dollars hiring people to teach kids about drugs. and over here you guys are trying to prove that theres no harm in doing drugs.
Maybe you should start thinking of how drugs affect you in other parts of your body aside from simply your FUCKING BRAIN.
Posted: Sat Dec 15, 2007 7:46 pm
by Ness
Somehow I don't think you even bothered to read my post.
Posted: Sat Dec 15, 2007 9:01 pm
by jaysawatzki
Ness wrote:jaysawatzki wrote:familyguy wrote:
looks like you just got proved wrong dumbfuck.
Ehh, he sure as hell isn't correct, but he's not entirely wrong. SOME drugs are OK if used CORRECTLY. But tell me is using a drug at all using it correctly other than using it for it's original intentions? I can see how MJ is used with out bad effects, because it really is meant to be "abused." Where taking regulated use of Cocaine for medical reasons can be ok, who the hell abuses Cocaine in regulation? no one. My point is, drugs are abused to the point of no return. Most people do studies on drugs to show their MEDICAL effect, not their recreational effects. Heroin is a great example of that. It is used to cure Morphine addiction, and when used to do so, it is perfectly fine. But when abused, and done over and over again in 20 times the normal dose, you have problems of vein trouble, etc. Same with LSD. Sure, once in a while it's fine, but when you start tampering, like most abusers do, you are going to get problems like the crudely put "holes in your brain." Anyway, all I am saying is no abuser is "safe" with their drug usage as this guy says.
I'm sorry, but you're just plain wrong all around. What you're saying is tantamount to saying that all black people are criminals, all Mexicans are lazy, and Chinese people can't drive. And MANY studies are done on the effects of recreational drug use. In fact, the studies that were done with LSD used doses *
FAR* above recreational doses. In fact, most studies done on recreational drug use use doses far, far above recreational doses with frequency far above normal use patterns. Heroin isn't used to treat morphine addiction, methadone and suboxone are used to treat opioid addiction of any kind, usually heroin. And even long-term opioid abuse is fine, ignoring the problems caused by using IV as your MOA. Not all users turn to IV use. there are a GREAT many responsible, safe drug users, myself included. And I am going to repeat, no amount of LSD use is going to burn holes in your brain or, in fact, cause ANY physical damage. In one government study, a person was given LSD every day for 77 days straight. He was fine. I'm sure that the person was permanently changed, but that is a result of the experience itself, NOT damage caused by the drug.
LMFAO!!!! See you are a typical drug user. I am sorry to say it but you are OBLIVIOUS to the real picture. Take it form me, I have a PhD in Neuroscience, and on top of that I usually am pretty drug oriented in my research. GET OFF THE DRUGS. Yeah guess what buddy, drugs aren't going to hurt you right NOW. Long term use of DXM for example causes olney's lesions. DRUGS ARE BAD. The only drug I can even see moderately decent it EATING WEED. Smoking one joint is about as bad as 5 cigarettes, and you know how bad cigs are for you. Most people in rehab say that they kept doing drugs and would tell themselves that it's all lies and they believe what they heard on Wiki, or off the streets, that drugs wont hurt you. Seriously it is time for one big news flash, THEY ARE BAD.
BTW: I have studied the use of Heroin as a cure for Morphine addiction after long term IV use of it. I THINK I would know.
Edit: :LSD has no medical purposes, that's why it is tested as a rec. drug dumb ass. If you want to get into how LSD is filtered through your body, and how many white blood cells can get attached and killed, or possibly how large doses can act as an MAO inhibitor and explode blood veins in your body, please let me know. But first, do some research.
EDIT again: Get off the steroids, maybe you will have less roid-rage.
Posted: Sat Dec 15, 2007 9:28 pm
by D13G0
NEVER in my life have I heard of a morphine addict going straight by using heroin. my mom is a transcriptonist in the medical field and knows her 2 sense about that. When mom's have babies when they are addicted to drugs, they use some weird name, i think it was methadone, to ween them of the addiction. Why would a doctor, even if in controlled form, try to rid a morphine addiction with heroin? That starts a whole new battle. Oh yeah, not saying you don't have one, but I'd like to see a pic of that phd. And ness has a point, drugs are neutral in the "good or bad for you" battle. I know someone who was addicted to meth in the 80's and is now a well known business man in my town, and builds and sells many houses. He has no physical or mental problems whatsoever. I'm with ness on this, drugs, when used responsibly, are ok. Then again, i'm just that 15 year old freshman.
Posted: Sat Dec 15, 2007 9:28 pm
by Ness
First off, Olney's Lesions are still technically theoretical. Plus, dissociatives are easily the most neurotoxic class of drugs, so yes, heavy dissociative use is bad for you. And LSD has PLENTY of potential use as a legitimate medicine, but research into that was stopped when it became a Schedule I controlled substance. As far as neurochemistry and drugs goes, I guarantee I can go toe to toe with you, whether you actually have a PhD in neurochemistry or not. Before I ever put anything into my body, I learn everything there is to know about it. As for the comparison between marijuana and tobacco, there really is very little comparison. For example, nicotine is absolutely horrible for you, whereas THC and cannabidol really aren't toxic. And you can not say "drugs are bad" or "drugs are not bad". You need to specify WHICH drug you're talking about. Example: Methamphetamine is horribly neurotoxic and really does a number on your body, which is why I never have and never will touch the stuff. THC on the other hand is non toxic. I'm going to say it AGAIN: I know exactly what I am talking about and when asked about a specific drug I will always state the good and the bad.
As for LSD as an MAO inhibitor, that is not something that I have ever come across in my research, but even if it were true, the MAO inhibition would have to be very slight and very short term, otherwise serotonin syndrome would be a common side effect of LSD use, and it is not.
Posted: Sat Dec 15, 2007 9:31 pm
by D13G0
@ ness's last post
Well, meth back in the day is not as horrible as it is now. It was still bad, yes, but now it's gone to shit.
EDIT:
Yes, it does do a number on your body, i'm not saying its harmless. The guy i know was down to what he weighed in highschool, when he was in his late 20's. He was indeed fucked up. the point i was making is that now day's its worse for you than it was.